Chromatin interaction mechanism of transcriptional control invivo
نویسندگان
چکیده
منابع مشابه
Chromatin interaction mechanism of transcriptional control in vivo.
We have used a kinetic analysis to distinguish possible mechanisms of activation of transcription of the different genes in the human beta globin locus. Based on in situ studies at the single-cell level we have previously suggested a dynamic mechanism of single genes alternately interacting with the locus control region (LCR) to activate transcription. However, those steady-state experiments di...
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1Department of Materials Science and Engineering, National Chiao Tung University, Hsinchu 300, Taiwan 2Department of Obstetrics and Gynecology, China Medical University and Hospital, 91 Hsueh Shih Road, Taichung 404, Taiwan 3College of Medicine, China Medical University, Taichung 40402, Taiwan 4 Institute of Chemical Kinetics & Combustion, Siberian Branch of Russian Academy of Sciences, Novosib...
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The long polycistronic transcription units of trypanosomes do not appear to be demarcated by the usual DNA motifs that punctuate transcription in familiar eukaryotes. In this issue of Genes & Development, Siegel and colleagues (pp. 1063-1076) describe a system for the demarcation of trypanosome transcription units based on the deposition and turnover of histone variants rather than on the bindi...
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ژورنال
عنوان ژورنال: The EMBO Journal
سال: 1998
ISSN: 1460-2075
DOI: 10.1093/emboj/17.20.6020